Bitten Jönsson - Jotunheim kennel - Δανία
Συγγραφέας, Sonia García



Understanding the prevalence of DCM in Dobermann. Some reflections

The results of the work of Wess et al. 2010, have enabled us to confront a crude reality, approximately 60% of European Dobermann population will die of DCM. Article of Dr. Reinhard Haberzettl, old Breed Warden for the East German Dobermann Verein, published in ”Das Schäferhund Magazin” Nr.6 Juni 2006, where he include two interesting data of prevalence of DCM for year 1989 (26.1%) and for year 2004 (46.3%) which provides new data about the historical evolution of the prevalence of DCM in the Dobermann European population. When we represent all data from two sources, a good correlation is shown which illustrate that Haberzettl data are valid.

This supposes that with actual mating system spread rate of DCM is about 1.5% by year and in 2020 the prevalence will be 72%!

In words of Dr. Reinhard Haberzettl (2002) : “The Doberman was created from mixtures of various breeds and half-breeds at the end of the 19th century. This genetic variety was a great health advantage. Up to approximately 1950, there were practically no hereditary health problems, worldwide. These qualities still remained in the populations of East Germany and Eastern Europe up to the nineties”.

An approximate lineal increase of prevalence over time leads to a quadratic increase in the number of affected during the initial spread of the DCM in the population between 1970-1988 and a more moderated increase trend (almost lineal) from 1989 to actual (figure 2). Simulations shown that, under a realistic scenario of 40 popular sires regarding the imbalance in the use of sires, the dissemination of the risk was indeed 4.4 times higher than under random mating conditions (Leroy. and Baumung, 2010). Parallel evolution of fraction of popular sire’s offspring (sires with more than 100 pups sired) and DCM affected dogs (figure 2) shows that initial critical spread of the DCM during period 1970-1988 coincides with the period of popularization of the breed and the overuse of popular dogs. After this period offspring of popular sires is less accentuated and also the increase of number of affected dogs.

Leroy. and Baumung, 2010 noted that linebreeding practice outside popular sire use not increase the risk to dissemination of genetic diseases. However mating trends in population of European Dobermann illustrate that inbreeding rate is based on popular sire practice as shows the good correlation between the average inbreeding coefficient (COI of seven generation pedigree) in the population and the fraction of population sided by popular sires (figure 3).